Recent quantum theory argues everything would indeed be set in stone (even without the existence of God) if not for random "supernatural" events intervening to change the trajectory of the universe. This intervention takes place at the smallest particle level and could affect a single particle or many particles concurrently.

https://www.newscientist.com/article/mg25033340-700-is-everything-predetermined-why-physicists-are-reviving-a-taboo-idea/

Quantum physics does not explain (as of yet) what triggers the supernatural intervention. But it is fair to say religious people attribute those interventions to God.

Of course, that gives rise to why does God intervene and how often?

Is God responding to prayer or the fact that the laws of science would lead the universe to a different endpoint then He intended or both.

Of course, that raises the question of whether prayer exists for us to influence God or as a means to arrive at the point, where we all pray "Thy will be done" in a world that can be impossible to comprehend.

All of this is even more complicated by the fact, that quantum physics believes not all random effects actually change the universe but may in fact give rise to simultaneous versions of the universe. As individuals, we experience the version of the universe that we occupy, but what if different versions of us were all operating independently in different versions of the universe?

It seems the more one studies quantum physics the more one begins to think (assuming one believes in God), that the Bible largely serves as a partial revelation of who God is. Not a complete revelation or even a detailed revelation, but more like "what you should know" revelation in order to feel that God is in control of the craziness going on around you. And there is something comforting in that.